3FHY
Crystal structure of D235N mutant of human pyridoxal kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pyridoxal kinase | polymer | 312 | 35142.3 | 2 | UniProt (O00764) Pfam (PF08543) | Homo sapiens (human) | Pyridoxine kinase |
| 2 | C, M (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, N (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E, O (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 5 | F, G, H, I, J... (A, B) | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
| 6 | AA, BA, K, L, W... (B, A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 8 | Chemie (MPD) | |||
| 7 | CA, DA (A, B) | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 312 (UniProt: O00764)
| PDB | External Database | Details |
|---|---|---|
| Asn 235 | Asp 235 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70284.6 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 3207.1 | |
| All* | Total formula weight | 73491.7 |
