3FHX
Crystal structure of D235A mutant of human pyridoxal kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pyridoxal kinase | polymer | 312 | 35099.3 | 2 | UniProt (O00764) Pfam (PF08543) | Homo sapiens (human) | Pyridoxine kinase |
| 2 | C, O (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, P (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E, Q (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 5 | F, R (A, B) | 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE | non-polymer | 167.2 | 2 | Chemie (PXL) | |||
| 6 | G, H, I, J, K... (A, B) | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
| 7 | N, X, Y, Z (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 4 | Chemie (MPD) | |||
| 8 | S (B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 9 | AA, BA (A, B) | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 312 (UniProt: O00764)
| PDB | External Database | Details |
|---|---|---|
| Ala 235 | Asp 235 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70198.5 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 3219.8 | |
| All* | Total formula weight | 73418.3 |
