3FHI
Crystal structure of a complex between the catalytic and regulatory (RI{alpha}) subunits of PKA
Replaces: 1U7EEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 350 | 40625.3 | 1 | UniProt (P05132) Pfam (PF00069) | Mus musculus (mouse) | PKA C-alpha |
| 2 | B (B) | cAMP-dependent protein kinase type I-alpha regulatory subunit | polymer | 154 | 17339.6 | 1 | UniProt (P00514) Pfam (PF00027) | Bos taurus (bovine cow domestic cattle domestic cow) | |
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 4 | D, E (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 1 - 350 (UniProt: P05132)
| PDB | External Database | Details |
|---|---|---|
| Ala 199 | Cys 200 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57964.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 616.1 | |
| All* | Total formula weight | 58580.9 |
