3FH7
Leukotriene A4 Hydrolase complexed with inhibitor 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leukotriene A-4 hydrolase | polymer | 611 | 69364.0 | 1 | UniProt (P09960) Pfam (PF17900) Pfam (PF01433) Pfam (PF09127) | Homo sapiens (Human) | Leukotriene A(4) hydrolase, LTA-4 hydrolase |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D, E (A) | YTTERBIUM (III) ION | non-polymer | 173.0 | 3 | Chemie (YB) | |||
| 4 | F (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | G (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 6 | H (A) | 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate | non-polymer | 388.9 | 1 | Chemie (25P) | |||
| 7 | I (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | J (A) | water | water | 18.0 | 525 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 69364.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1193.6 | |
| All* | Total formula weight | 70557.6 |
