3FFI
HIV-1 RT with pyridone non-nucleoside inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Reverse transcriptase/ribonuclease H | polymer | 561 | 64694.1 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | HIV-1 M:B_HXB2R (HIV-1) | p66 RT |
| 2 | B | RT p51 | polymer | 441 | 51530.2 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) In PDB | HIV-1 M:B_HXB2R (HIV-1) | |
| 3 | A | 3-chloro-5-({6-[2-(3,4-dihydroisoquinolin-2(1H)-yl)-2-oxoethyl]-3-(dimethylamino)-2-oxo-1,2-dihydropyridin-4-yl}oxy)benzonitrile | non-polymer | 462.9 | 1 | Chemie (3OB) | |||
| 4 | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 1 - 560 (UniProt: P04585)
B: 1 - 440 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116224.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 462.9 | |
| All* | Total formula weight | 116687.3 |
