3FFG
Factor XA in complex with the inhibitor (R)-6-(2'-((3- HYDROXYPYRROLIDIN-1-YL)METHYL)BIPHENYL-4-YL)-1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-3-(TRIFLUOROMETHYL)-5,6-DIHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN- 7(4H)-ONE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Coagulation factor X, heavy chain | polymer | 234 | 26447.1 | 1 | UniProt (P00742) Pfam (PF00089) In PDB | Homo sapiens (human) | factor Xa heavy chain, Stuart factor, Stuart-Prower factor, Factor X heavy chain |
| 2 | L | Coagulation factor X, light chain | polymer | 52 | 5589.2 | 1 | UniProt (P00742) Pfam (PF14670) In PDB | Homo sapiens (human) | factor X light chain, Stuart factor, Stuart-Prower factor |
| 3 | A | (R)-6-(2'-((3-hydroxypyrrolidin-1-yl)methyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one | non-polymer | 615.6 | 1 | Chemie (FFG) | |||
| 4 | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32036.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 615.6 | |
| All* | Total formula weight | 32651.9 |
