3FEJ
Design and biological evaluation of novel, balanced dual PPARa/g agonists
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 271 | 30997.0 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma, Nuclear receptor subfamily 1 group C member 3 |
| 2 | B (B) | peptide motif 3 of Nuclear receptor coactivator 1 | polymer | 13 | 1471.7 | 1 | UniProt (Q15788) | SRC-1 Coactivator protein peptide motif 3 | |
| 3 | C (A) | (2S)-3-(4-{[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methoxy}-2-methylphenyl)-2-ethoxypropanoic acid | non-polymer | 431.9 | 1 | Chemie (CTM) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 259 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32468.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 431.9 | |
| All* | Total formula weight | 32900.7 |
