3FEI
Design and biological evaluation of novel, balanced dual PPARa/g agonists
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peroxisome proliferator-activated receptor alpha | polymer | 267 | 30270.4 | 1 | UniProt (Q07869) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-alpha, Nuclear receptor subfamily 1 group C member 1 |
| 2 | Z | Peptide motif 5 of Nuclear receptor coactivator 1 | polymer | 13 | 1660.9 | 1 | UniProt (Q15788) In PDB | SRC-1 Coactivator protein motif 5 | |
| 3 | A | (2S)-3-(4-{[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methoxy}-2-methylphenyl)-2-ethoxypropanoic acid | non-polymer | 431.9 | 1 | Chemie (CTM) | |||
| 4 | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31931.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 431.9 | |
| All* | Total formula weight | 32363.2 |
