3FEG
Crystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Choline/ethanolamine kinase | polymer | 379 | 44002.6 | 1 | UniProt (Q9Y259) Pfam (PF01633) | Homo sapiens (human) | Choline kinase beta, CK, Ethanolamine kinase, EK |
| 2 | B (A) | (2S)-2-[4'-({dimethyl[2-(phosphonooxy)ethyl]ammonio}acetyl)biphenyl-4-yl]-2-hydroxy-4,4-dimethylmorpholin-4-ium | non-polymer | 494.5 | 1 | Chemie (HC7) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | E (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 6 | F (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | G, H (A) | UNKNOWN ATOM OR ION | non-polymer | 2 | Chemie (UNX) | ||||
| 8 | I (A) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A: 35 - 395 (UniProt: Q9Y259)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | - | expression tag |
| Ser 18 | - | expression tag |
| Ser 19 | - | expression tag |
| His 20 | - | expression tag |
| His 21 | - | expression tag |
| His 22 | - | expression tag |
| His 23 | - | expression tag |
| His 24 | - | expression tag |
| His 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Leu 29 | - | expression tag |
| Val 30 | - | expression tag |
| Pro 31 | - | expression tag |
| Arg 32 | - | expression tag |
| Gly 33 | - | expression tag |
| Ser 34 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44002.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1389.3 | |
| All* | Total formula weight | 45391.9 |
