3FEG
Crystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Choline/ethanolamine kinase | polymer | 379 | 44002.6 | 1 | UniProt (Q9Y259) Pfam (PF01633) | Homo sapiens (human) | Choline kinase beta, CK, Ethanolamine kinase, EK |
| 2 | B (A) | (2S)-2-[4'-({dimethyl[2-(phosphonooxy)ethyl]ammonio}acetyl)biphenyl-4-yl]-2-hydroxy-4,4-dimethylmorpholin-4-ium | non-polymer | 494.5 | 1 | Chemie (HC7) PubChem (25113187) PubChem (45259046) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | E (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 6 | F (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 7 | G, H (A) | UNKNOWN ATOM OR ION | non-polymer | 2 | Chemie (UNX) | ||||
| 8 | I (A) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A: 35 - 395 (UniProt: Q9Y259)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | - | expression tag |
| Ser 18 | - | expression tag |
| Ser 19 | - | expression tag |
| His 20 | - | expression tag |
| His 21 | - | expression tag |
| His 22 | - | expression tag |
| His 23 | - | expression tag |
| His 24 | - | expression tag |
| His 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Leu 29 | - | expression tag |
| Val 30 | - | expression tag |
| Pro 31 | - | expression tag |
| Arg 32 | - | expression tag |
| Gly 33 | - | expression tag |
| Ser 34 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44002.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1389.3 | |
| All* | Total formula weight | 45391.9 |
