3FE3
Crystal structure of the kinase MARK3/Par-1: T211A-S215A double mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | MAP/microtubule affinity-regulating kinase 3 | polymer | 328 | 37619.6 | 2 | UniProt (P27448) Pfam (PF00069) Pfam (PF00627) | Homo sapiens (Human) | Cdc25C-associated protein kinase 1, C-TAK1, cTAK1, Serine/threonine protein kinase p78, Ser/Thr protein kinase PAR-1, Protein kinase STK10 |
2 | C, D (A, B) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence modifications
A, B: 41 - 367 (UniProt: P27448)
PDB | External Database | Details |
---|---|---|
Gly 40 | - | expression tag |
Ala 211 | Thr 211 | engineered mutation |
Ala 215 | Ser 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 75239.2 | |
All* | Total formula weight | 75239.2 |