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3FE3

Crystal structure of the kinase MARK3/Par-1: T211A-S215A double mutant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
MAP/microtubule affinity-regulating kinase 3polymer32837619.62UniProt (P27448)
Pfam (PF00069)
Pfam (PF00627)
Homo sapiens (Human)Cdc25C-associated protein kinase 1, C-TAK1, cTAK1, Serine/threonine protein kinase p78, Ser/Thr protein kinase PAR-1, Protein kinase STK10
2C, D
(A, B)
waterwater18.0398Chemie (HOH)
Sequence modifications
A, B: 41 - 367 (UniProt: P27448)
PDBExternal DatabaseDetails
Gly 40-expression tag
Ala 211Thr 211engineered mutation
Ala 215Ser 215engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight75239.2
All*Total formula weight75239.2
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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