3FBX

Crystal structure of the lysosomal 66.3 kDa protein from mouse solved by S-SAD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Putative phospholipase B-like 2	polymer	559	63233.3	1	UniProt (Q3TCN2) Pfam (PF04916) In PDB	Mus musculus (mouse)	66.3 kDa protein, Lamina ancestor homolog 2, LAMA-like protein 2, 76 kDa protein, p76, Putative phospholipase B-like 2 28 kDa form, Putative phospholipase B-like 2 40 kDa form, Putative phospholipase B-like 2 15 kDa form
2	B	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
3	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
4	A	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
5	A	XENON	non-polymer		131.3	1	Chemie (XE)
6	A	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
7	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
8	A	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
9	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
10		water	water		18.0	294	Chemie (HOH)

Sequence modifications

A: 47 - 594 (UniProt: Q3TCN2)

PDB	External Database	Details
Gly 595	-	expression tag
Arg 596	-	expression tag
Gly 597	-	expression tag
Ser 598	-	expression tag
His 599	-	expression tag
His 600	-	expression tag
His 601	-	expression tag
His 602	-	expression tag
His 603	-	expression tag
His 604	-	expression tag
Gly 605	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	63233.3
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	12
	Total formula weight	1691.9
All*	Total formula weight	65349.5

*Water molecules are not included.