3FAA
Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | TGF-beta receptor type-1 | polymer | 342 | 38920.6 | 5 | UniProt (P36897) Pfam (PF08515) Pfam (PF00069) | Homo sapiens | TGF-beta receptor type I, TGFR-1, TGF-beta type I receptor, Transforming growth factor-beta receptor type I, TbetaR-I, Serine/threonine-protein kinase receptor R4, SKR4, Activin receptor-like kinase 5, ALK-5 |
| 2 | F, J, N, P, T (A, B, C, D, E) | N-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1H-imidazol-2-yl]acetamide | non-polymer | 362.4 | 5 | Chemie (55F) | |||
| 3 | G, H, I, K, L... (A, B, C, D, E) | PHOSPHATE ION | non-polymer | 95.0 | 13 | Chemie (PO4) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 194603.2 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3046.4 | |
| All* | Total formula weight | 197649.6 |
