3F62
Crystal Structure of Human IL-18 in complex with Ectromelia virus IL-18 Binding Protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin 18 binding protein | polymer | 109 | 12368.0 | 1 | UniProt (Q9IW12) Pfam (PF05566) UniProt (by SIFTS) (Q85319) | Ectromelia virus | |
| 2 | B (B) | Interleukin-18 | polymer | 158 | 18232.5 | 1 | UniProt (Q14116) Pfam (PF00340) | Homo sapiens (human) | IL-18, Interferon-gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma, Iboctadekin |
| 3 | C, D (A, B) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A: 21 - 126 (UniProt: Q9IW12)
B: 1 - 157 (UniProt: Q14116)
| PDB | External Database | Details |
|---|---|---|
| Gly 18 | - | expression tag |
| Ala 19 | - | expression tag |
| Met 20 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 38 | Cys 74 | engineered mutation |
| Ser 68 | Cys 104 | engineered mutation |
| Ser 76 | Cys 112 | engineered mutation |
| Ser 127 | Cys 163 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30600.5 | |
| All* | Total formula weight | 30600.5 |
