3EZR
CDK-2 with indazole inhibitor 17 bound at its active site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cell division protein kinase 2 | polymer | 300 | 34120.6 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (Human) | p33 protein kinase |
| 2 | A | 3-methoxy-4-{3-[4-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline | non-polymer | 453.5 | 2 | Chemie (EZR) | |||
| 3 | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34120.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 907.1 | |
| All* | Total formula weight | 35027.7 |
