3EYG
Crystal structures of JAK1 and JAK2 inhibitor complexes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase | polymer | 290 | 33489.2 | 1 | UniProt (Q59GQ2) Pfam (PF07714) UniProt (by SIFTS) (P23458) | Homo sapiens (human) | |
| 2 | B (A) | 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile | non-polymer | 312.4 | 1 | Chemie (MI1) | |||
| 3 | C (A) | water | water | 18.0 | 265 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33489.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 312.4 | |
| All* | Total formula weight | 33801.6 |
