3EYC
New crystal structure of human tear lipocalin in complex with 1,4-butanediol in space group P21
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Lipocalin-1 | polymer | 162 | 17949.2 | 4 | UniProt (P31025) Pfam (PF00061) In PDB | Homo sapiens (human) | Von Ebner gland protein, VEG protein, Tear prealbumin, TP, Tear lipocalin, Tlc |
| 2 | A, B, C, D | 1,4-BUTANEDIOL | non-polymer | 90.1 | 4 | Chemie (BU1) | |||
| 3 | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 5 - 158 (UniProt: P31025)
| PDB | External Database | Details |
|---|---|---|
| Ser 101 | Cys 119 | engineered mutation |
| Ala 158 | Asp 176 | engineered mutation |
| Trp 159 | - | expression tag |
| Ser 160 | - | expression tag |
| His 161 | - | expression tag |
| Pro 162 | - | expression tag |
| Gln 163 | - | expression tag |
| Phe 164 | - | expression tag |
| Glu 165 | - | expression tag |
| Lys 166 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71796.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 360.5 | |
| All* | Total formula weight | 72157.2 |
