3ETO
2 Angstrom Xray structure of the NOTCH1 Negative Regulatory Region (NRR)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Neurogenic locus notch homolog protein 1 | polymer | 242 | 26792.7 | 2 | UniProt (P46531) Pfam (PF00066) Pfam (PF06816) Pfam (PF07684) | Homo sapiens | Notch 1, hN1, Translocation-associated notch protein TAN-1 |
| 2 | C, D, E, K, L... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 3 | F, N (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | G, H, I, J, O... (A, B) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 5 | R, S (A, B) | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A, B: 1447 - 1734 (UniProt: P46531)
| PDB | External Database | Details |
|---|---|---|
| Gly 1446 | - | expression tag |
| - | Arg 1623 | deletion |
| - | Glu 1624 | deletion |
| - | Glu 1625 | deletion |
| - | Glu 1626 | deletion |
| - | Leu 1627 | deletion |
| - | Arg 1628 | deletion |
| - | Lys 1629 | deletion |
| - | His 1630 | deletion |
| - | Pro 1631 | deletion |
| - | Ile 1632 | deletion |
| - | Lys 1633 | deletion |
| - | Arg 1634 | deletion |
| - | Ala 1635 | deletion |
| - | Ala 1636 | deletion |
| - | Glu 1637 | deletion |
| - | Gly 1638 | deletion |
| - | Trp 1639 | deletion |
| - | Ala 1640 | deletion |
| - | Ala 1641 | deletion |
| - | Pro 1642 | deletion |
| - | Asp 1643 | deletion |
| - | Ala 1644 | deletion |
| - | Leu 1645 | deletion |
| - | Leu 1646 | deletion |
| - | Gly 1647 | deletion |
| - | Gln 1648 | deletion |
| - | Val 1649 | deletion |
| - | Lys 1650 | deletion |
| - | Ala 1651 | deletion |
| - | Ser 1652 | deletion |
| - | Leu 1653 | deletion |
| - | Leu 1654 | deletion |
| - | Pro 1655 | deletion |
| - | Gly 1656 | deletion |
| - | Gly 1657 | deletion |
| - | Ser 1658 | deletion |
| - | Glu 1659 | deletion |
| - | Gly 1660 | deletion |
| - | Gly 1661 | deletion |
| - | Arg 1662 | deletion |
| - | Arg 1663 | deletion |
| - | Arg 1664 | deletion |
| - | Arg 1665 | deletion |
| - | Glu 1666 | deletion |
| - | Leu 1667 | deletion |
| - | Asp 1668 | deletion |
| - | Pro 1669 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53585.4 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 956.0 | |
| All* | Total formula weight | 54541.4 |
