3ET7
Crystal structure of PYK2 complexed with PF-2318841
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Protein tyrosine kinase 2 beta | polymer | 277 | 32190.3 | 1 | UniProt (Q14289) Pfam (PF07714) In PDB | Homo sapiens (human) | Proline-rich Tyrosine Kinase 2, Focal adhesion kinase 2, FADK 2, Proline-rich tyrosine kinase 2, Cell adhesion kinase beta, CAK beta, Calcium-dependent tyrosine kinase, CADTK, Related adhesion focal tyrosine kinase, RAFTK |
| 2 | A | 5-{[4-{[2-(pyrrolidin-1-ylsulfonyl)benzyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,3-dihydro-2H-indol-2-one | non-polymer | 530.5 | 1 | Chemie (349) | |||
| 3 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32190.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 625.5 | |
| All* | Total formula weight | 32815.8 |
