3ET0

Structure of PPARgamma with 3-(5-Methoxy-1H-indol-3-yl)-propionic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Peroxisome proliferator-activated receptor gamma	polymer	292	33375.7	2	UniProt (P37231) Pfam (PF00104)	Homo sapiens (human)	PPAR-gamma, Nuclear receptor subfamily 1 group C member 3
2	C (A)	3-(5-methoxy-1H-indol-3-yl)propanoic acid	non-polymer		219.2	1	Chemie (ET0)
3	D (B)	alpha-D-glucopyranose	non-polymer		180.2	1	Chemie (GLC)
4	E, F (A, B)	water	water		18.0	98	Chemie (HOH)

Sequence modifications

A, B: 207 - 477 (UniProt: P37231)

PDB	External Database	Details
Met 186	-	expression tag
Gly 187	-	expression tag
Ser 188	-	expression tag
Ser 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
His 192	-	expression tag
His 193	-	expression tag
His 194	-	expression tag
His 195	-	expression tag
Ser 196	-	expression tag
Ser 197	-	expression tag
Gly 198	-	expression tag
Leu 199	-	expression tag
Val 200	-	expression tag
Pro 201	-	expression tag
Arg 202	-	expression tag
Gly 203	-	expression tag
Ser 204	-	expression tag
His 205	-	expression tag
Met 206	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66751.4
Non-Polymers*	Number of molecules	2
	Total formula weight	399.4
All*	Total formula weight	67150.8

*Water molecules are not included.