3ERZ

Directing Noble Metal Ion Chemistry within a Designed Ferritin Protein. Mercury Ions on the Three-Fold Channel

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Ferritin heavy chain	polymer	183	21140.6	12	UniProt (P02794) Pfam (PF00210) In PDB	Homo sapiens (human)	Ferritin H subunit, Cell proliferation-inducing gene 15 protein
2	G, H, I, A, K...	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	11	Chemie (MPD)
3	F, G, H, I, J...	MERCURY (II) ION	non-polymer		200.6	12	Chemie (HG)
4	G, J, A	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
5	G, H, I, A, B	ZINC ION	non-polymer		65.4	5	Chemie (ZN)
6		water	water		18.0	207	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 0 - 182 (UniProt: P02794)

PDB	External Database	Details
Asp 13	His 14	engineered mutation
Cys 64	Glu 65	engineered mutation
Arg 90	Cys 91	engineered mutation
Ala 102	Cys 103	engineered mutation
Gln 105	His 106	engineered mutation
Cys 140	Glu 141	engineered mutation
Cys 143	Lys 144	engineered mutation
Cys 147	Glu 148	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	253687.4
Non-Polymers*	Number of molecules	31
	Total formula weight	4154.3
All*	Total formula weight	257841.7

*Water molecules are not included.