3EQV
Crystal structure of penicillin-binding protein 2 from Neisseria gonorrhoeae containing four mutations associated with penicillin resistance
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Penicillin-binding protein 2 | polymer | 542 | 59109.0 | 2 | UniProt (P08149) Pfam (PF03717) Pfam (PF00905) | Neisseria gonorrhoeae | PBP-2 |
| 2 | C, D, E, F, G... (A, B) | SULFATE ION | non-polymer | 96.1 | 15 | Chemie (SO4) | |||
| 3 | I, S (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | T, U (A, B) | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence modifications
A, B: 44 - 581 (UniProt: P08149)
| PDB | External Database | Details |
|---|---|---|
| Gly 40 | - | expression tag |
| Ser 41 | - | expression tag |
| Gly 42 | - | expression tag |
| Gly 43 | - | expression tag |
| Leu 504 | Phe 504 | engineered mutation |
| Val 510 | Ala 510 | engineered mutation |
| Gly 516 | Ala 516 | engineered mutation |
| Ser 551 | Pro 551 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 118217.9 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1625.1 | |
| All* | Total formula weight | 119843.0 |
