3EQS

Crystal structure of human MDM2 in complex with a 12-mer peptide inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	E3 ubiquitin-protein ligase Mdm2	polymer	85	10044.9	1	UniProt (Q00987) Pfam (PF02201) In PDB		p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2
2	B	12-mer peptide inhibitor	polymer	12	1427.6	1
3	A	GUANIDINE	non-polymer		59.1	1	Chemie (GAI)
4		water	water		18.0	117	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	11472.4
Non-Polymers*	Number of molecules	1
	Total formula weight	59.1
All*	Total formula weight	11531.5

*Water molecules are not included.