3EQS
Crystal structure of human MDM2 in complex with a 12-mer peptide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase Mdm2 | polymer | 85 | 10044.9 | 1 | UniProt (Q00987) Pfam (PF02201) | p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2 | |
| 2 | B (B) | 12-mer peptide inhibitor | polymer | 12 | 1427.6 | 1 | |||
| 3 | C (A) | GUANIDINE | non-polymer | 59.1 | 1 | Chemie (GAI) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 117 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 11472.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 59.1 | |
| All* | Total formula weight | 11531.5 |
