3EQR

Crystal Structure of Ack1 with compound T74

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Activated CDC42 kinase 1	polymer	276	31538.4	2	UniProt (Q07912) Pfam (PF07714)	Homo sapiens (human)	ACK-1, Tyrosine kinase non-receptor protein 2
2	C, E (A, B)	N~3~-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-N~6~-(4-piperazin-1-ylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine	non-polymer		514.7	2	Chemie (T74)
3	D (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	F, G (A, B)	water	water		18.0	307	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63076.8
Non-Polymers*	Number of molecules	3
	Total formula weight	1064.8
All*	Total formula weight	64141.6

*Water molecules are not included.