3EPF
CryoEM structure of poliovirus receptor bound to poliovirus type 2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | R | Poliovirus receptor | polymer | 213 | 23330.5 | 1 | UniProt (P15151) Pfam (PF07686) Pfam (PF08205) In PDB | Homo sapiens (human) | Nectin-like protein 5, Necl-5 |
2 | 1 | Protein VP1 | polymer | 278 | 30734.5 | 1 | UniProt (P06210) Pfam (PF00073) In PDB | Poliovirus type 2 | |
3 | 2 | Protein VP2 | polymer | 262 | 29045.8 | 1 | UniProt (P06210) Pfam (PF00073) In PDB | Poliovirus type 2 | |
4 | 4 | Protein VP4 | polymer | 68 | 7347.0 | 1 | UniProt (P06210) Pfam (PF02226) In PDB | Poliovirus type 2 | |
5 | 3 | Protein VP3 | polymer | 235 | 26115.9 | 1 | UniProt (P06210) Pfam (PF00073) In PDB | Poliovirus type 2 | |
6 | 1 | 1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE | non-polymer | 423.7 | 1 | Chemie (SC4) | |||
7 | 4 | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | |||
8 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
R: 30 - 242 (UniProt: P15151)
2: 10 - 271 (UniProt: P06210)
PDB | External Database | Details |
---|---|---|
Asp 105 | Asn 105 | engineered mutation |
Ser 120 | Asn 120 | engineered mutation |
Gln 188 | Asn 188 | engineered mutation |
Gln 218 | Asn 218 | engineered mutation |
Ser 237 | Asn 237 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Val 11 | Asp 80 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 116573.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 652.1 | |
All* | Total formula weight | 117225.8 |