3EPF

CryoEM structure of poliovirus receptor bound to poliovirus type 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	R	Poliovirus receptor	polymer	213	23330.5	1	UniProt (P15151) Pfam (PF07686) Pfam (PF08205) In PDB	Homo sapiens (human)	Nectin-like protein 5, Necl-5
2	1	Protein VP1	polymer	278	30734.5	1	UniProt (P06210) Pfam (PF00073) In PDB	Poliovirus type 2
3	2	Protein VP2	polymer	262	29045.8	1	UniProt (P06210) Pfam (PF00073) In PDB	Poliovirus type 2
4	4	Protein VP4	polymer	68	7347.0	1	UniProt (P06210) Pfam (PF02226) In PDB	Poliovirus type 2
5	3	Protein VP3	polymer	235	26115.9	1	UniProt (P06210) Pfam (PF00073) In PDB	Poliovirus type 2
6	1	1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE	non-polymer		423.7	1	Chemie (SC4)
7	4	MYRISTIC ACID	non-polymer		228.4	1	Chemie (MYR)
8		water	water		18.0	271	Chemie (HOH)

Sequence modifications

R: 30 - 242 (UniProt: P15151)

PDB	External Database	Details
Asp 105	Asn 105	engineered mutation
Ser 120	Asn 120	engineered mutation
Gln 188	Asn 188	engineered mutation
Gln 218	Asn 218	engineered mutation
Ser 237	Asn 237	engineered mutation

2: 10 - 271 (UniProt: P06210)

PDB	External Database	Details
Val 11	Asp 80	conflict

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	116573.7
Non-Polymers*	Number of molecules	2
	Total formula weight	652.1
All*	Total formula weight	117225.8

*Water molecules are not included.