3EPD
CryoEM structure of poliovirus receptor bound to poliovirus type 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | R | Poliovirus receptor | polymer | 213 | 23330.5 | 1 | UniProt (P15151) Pfam (PF07686) Pfam (PF08205) In PDB | Homo sapiens (human) | Nectin-like protein 5, Necl-5 |
| 2 | 0 | Poliovirus Type3 peptide | polymer | 4 | 446.5 | 1 | |||
| 3 | 1 | protein VP1 | polymer | 279 | 31358.2 | 1 | UniProt (Q8B3S0) Pfam (PF00073) UniProt (by SIFTS) (A0A0B6VQW0) In PDB | Human poliovirus 3 | |
| 4 | 2 | protein VP2 | polymer | 266 | 29643.4 | 1 | UniProt (Q8B3S0) Pfam (PF00073) UniProt (by SIFTS) (P03302) In PDB | Human poliovirus 3 | |
| 5 | 4 | protein VP4 | polymer | 68 | 7320.9 | 1 | UniProt (Q8B3S0) Pfam (PF02226) UniProt (by SIFTS) (P03302) In PDB | Human poliovirus 3 | |
| 6 | 3 | protein VP3 | polymer | 235 | 25950.7 | 1 | UniProt (Q8B3S0) Pfam (PF00073) UniProt (by SIFTS) (A0A0B4MVN6) In PDB | Human poliovirus 3 | |
| 7 | 1 | SPHINGOSINE | non-polymer | 299.5 | 1 | Chemie (SPH) | |||
| 8 | 4 | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) |
Sequence modifications
R: 30 - 242 (UniProt: P15151)
| PDB | External Database | Details |
|---|---|---|
| Asp 105 | Asn 105 | engineered mutation |
| Ser 120 | Asn 120 | engineered mutation |
| Gln 188 | Asn 188 | engineered mutation |
| Gln 218 | Asn 218 | engineered mutation |
| Ser 237 | Asn 237 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 118050.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 527.9 | |
| All* | Total formula weight | 118578.1 |
