3EPC
CryoEM structure of poliovirus receptor bound to poliovirus type 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | R | Poliovirus receptor | polymer | 213 | 23330.5 | 1 | UniProt (P15151) Pfam (PF07686) Pfam (PF08205) In PDB | Homo sapiens (human) | Nectin-like protein 5, Necl-5 |
2 | 1 | Protein VP1 | polymer | 283 | 31455.3 | 1 | UniProt (P03300) Pfam (PF00073) In PDB | Human poliovirus 1 Mahoney | |
3 | 2 | Protein VP2 | polymer | 268 | 29664.3 | 1 | UniProt (P03300) Pfam (PF00073) In PDB | Human poliovirus 1 Mahoney | |
4 | 4 | Protein VP4 | polymer | 68 | 7393.1 | 1 | UniProt (P03300) Pfam (PF02226) In PDB | Human poliovirus 1 Mahoney | |
5 | 3 | Protein VP3 | polymer | 235 | 26235.1 | 1 | UniProt (P03300) Pfam (PF00073) In PDB | Human poliovirus 1 Mahoney | |
6 | 1 | SPHINGOSINE | non-polymer | 299.5 | 1 | Chemie (SPH) | |||
7 | 4 | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) |
Sequence modifications
R: 30 - 242 (UniProt: P15151)
3: 1 - 235 (UniProt: P03300)
PDB | External Database | Details |
---|---|---|
Asp 105 | Asn 105 | engineered mutation |
Ser 120 | Asn 120 | engineered mutation |
Gln 188 | Asn 188 | engineered mutation |
Gln 218 | Asn 218 | engineered mutation |
Ser 237 | Asn 237 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 123 | Phe 464 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 118078.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 527.9 | |
All* | Total formula weight | 118606.2 |