3EPC
CryoEM structure of poliovirus receptor bound to poliovirus type 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Poliovirus receptor | polymer | 213 | 23330.5 | 1 | UniProt (P15151) Pfam (PF07686) Pfam (PF08205) | Homo sapiens (human) | Nectin-like protein 5, Necl-5 |
| 2 | B (1) | Protein VP1 | polymer | 283 | 31455.3 | 1 | UniProt (P03300) Pfam (PF00073) | Human poliovirus 1 Mahoney | |
| 3 | C (2) | Protein VP2 | polymer | 268 | 29664.3 | 1 | UniProt (P03300) Pfam (PF00073) | Human poliovirus 1 Mahoney | |
| 4 | D (4) | Protein VP4 | polymer | 68 | 7393.1 | 1 | UniProt (P03300) Pfam (PF02226) | Human poliovirus 1 Mahoney | |
| 5 | E (3) | Protein VP3 | polymer | 235 | 26235.1 | 1 | UniProt (P03300) Pfam (PF00073) | Human poliovirus 1 Mahoney | |
| 6 | F (1) | SPHINGOSINE | non-polymer | 299.5 | 1 | Chemie (SPH) | |||
| 7 | G (4) | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) |
Sequence modifications
R: 30 - 242 (UniProt: P15151)
3: 1 - 235 (UniProt: P03300)
| PDB | External Database | Details |
|---|---|---|
| Asp 105 | Asn 105 | engineered mutation |
| Ser 120 | Asn 120 | engineered mutation |
| Gln 188 | Asn 188 | engineered mutation |
| Gln 218 | Asn 218 | engineered mutation |
| Ser 237 | Asn 237 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 123 | Phe 464 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 118078.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 527.9 | |
| All* | Total formula weight | 118606.2 |
