3EPC

CryoEM structure of poliovirus receptor bound to poliovirus type 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	R	Poliovirus receptor	polymer	213	23330.5	1	UniProt (P15151) Pfam (PF07686) Pfam (PF08205) In PDB	Homo sapiens (human)	Nectin-like protein 5, Necl-5
2	1	Protein VP1	polymer	283	31455.3	1	UniProt (P03300) Pfam (PF00073) In PDB	Human poliovirus 1 Mahoney
3	2	Protein VP2	polymer	268	29664.3	1	UniProt (P03300) Pfam (PF00073) In PDB	Human poliovirus 1 Mahoney
4	4	Protein VP4	polymer	68	7393.1	1	UniProt (P03300) Pfam (PF02226) In PDB	Human poliovirus 1 Mahoney
5	3	Protein VP3	polymer	235	26235.1	1	UniProt (P03300) Pfam (PF00073) In PDB	Human poliovirus 1 Mahoney
6	1	SPHINGOSINE	non-polymer		299.5	1	Chemie (SPH)
7	4	MYRISTIC ACID	non-polymer		228.4	1	Chemie (MYR)

Sequence modifications

R: 30 - 242 (UniProt: P15151)

PDB	External Database	Details
Asp 105	Asn 105	engineered mutation
Ser 120	Asn 120	engineered mutation
Gln 188	Asn 188	engineered mutation
Gln 218	Asn 218	engineered mutation
Ser 237	Asn 237	engineered mutation

3: 1 - 235 (UniProt: P03300)

PDB	External Database	Details
Ser 123	Phe 464	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	118078.3
Non-Polymers*	Number of molecules	2
	Total formula weight	527.9
All*	Total formula weight	118606.2

*Water molecules are not included.