3EOA

Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form I

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	L, A	Efalizumab Fab fragment, light chain	polymer	214	23436.1	2		Homo sapiens
2	H, B	Efalizumab Fab fragment, heavy chain	polymer	220	23751.6	2		Homo sapiens
3	I, J	Integrin alpha-L	polymer	181	20678.7	2	UniProt (P20701) Pfam (PF00092) In PDB	Homo sapiens (human)	Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD11 antigen-like family member A
4		water	water		18.0	356	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	135732.7
All*	Total formula weight	135732.7

*Water molecules are not included.