3ENZ

Arsenolytic structure of Plasmodium falciparum purine nucleoside phosphorylase with hypoxanthine, ribose and arsenate ion

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Purine nucleoside phosphorylase	polymer	253	27962.3	6	UniProt (Q8I3X4) Pfam (PF01048)	Plasmodium falciparum
2	G, HA, R, RA, VA... (A, D, B, E, F...)	HYPOXANTHINE	non-polymer		136.1	6	Chemie (HPA)
3	H, IA, S, SA, WA... (A, D, B, E, F...)	1,4-anhydro-D-ribitol	non-polymer		134.1	6	Chemie (R1X) PubChem (952) PubChem (104501) PubChem (45254006) PubChem (53947339) PubChem (54022353) PubChem (54360137) PubChem (57116266) PubChem (57212685) PubChem (57224994) PubChem (57298976) PubChem (68034339) PubChem (70137932) PubChem (57249592) PubChem (90700823) PubChem (10931473) PubChem (12444980) PubChem (12444981) PubChem (12444982) PubChem (118067893) PubChem (12444984) PubChem (126611603) PubChem (156225518) PubChem (12444983)
4	I, JA, T, TA, XA... (A, D, B, E, F...)	ARSENATE	non-polymer		138.9	6	Chemie (ART) PubChem (27401)
5	AA, AB, BA, CA, DA... (C, F, A, D, B...)	FORMIC ACID	non-polymer		46.0	24	Chemie (FMT) PubChem (284)
6	GA, PA, Q, QA, W (C, D, A, B)	SODIUM ION	non-polymer		23.0	5	Chemie (NA) PubChem (923)
7	BB, CB, DB, EB, FB... (A, B, C, D, E...)	water	water		18.0	558	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 245 (UniProt: Q8I3X4)

PDB	External Database	Details
Leu 246	-	expression tag
Glu 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	167773.9
Non-Polymers*	Number of molecules	47
	Total formula weight	3674.5
All*	Total formula weight	171448.4

*Water molecules are not included.