3ELJ
Jnk1 complexed with a bis-anilino-pyrrolopyrimidine inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 8 | polymer | 369 | 42508.2 | 1 | UniProt (P45983) Pfam (PF00069) | Homo sapiens (human) | Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, JNK-46 |
| 2 | B (A) | 2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide | non-polymer | 484.5 | 1 | Chemie (GS7) | |||
| 3 | C (A) | water | water | 18.0 | 325 | Chemie (HOH) |
Sequence modifications
A: 1 - 364 (UniProt: P45983)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42508.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 484.5 | |
| All* | Total formula weight | 42992.7 |
