3ELC
Crystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | polymer | 165 | 17576.3 | 3 | UniProt (P62617) Pfam (PF02542) | Escherichia coli K-12 | MECPS, MECDP-synthase |
| 2 | D, F, H (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E, G, I (A, B, C) | 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-pyrimidin-2-one | non-polymer | 261.2 | 3 | Chemie (F01) | |||
| 4 | J (C) | GERANYL DIPHOSPHATE | non-polymer | 314.2 | 1 | Chemie (GPP) | |||
| 5 | K, L, M (A, B, C) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 159 (UniProt: P62617)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| His -3 | - | expression tag |
| Met -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Glu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 52728.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1294.1 | |
| All* | Total formula weight | 54022.9 |
