3EL1
Crystal Structure of wild-type HIV protease in complex with the inhibitor, Atazanavir
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Protease | polymer | 99 | 10801.8 | 2 | UniProt (P03369) Pfam (PF00077) In PDB | HIV-1 M:B_ARV2/SF2 (HIV-1) | Retropepsin, PR |
2 | A | (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5, 6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER | non-polymer | 704.9 | 1 | Chemie (DR7) | |||
3 | A, B | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
4 | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P03369)
PDB | External Database | Details |
---|---|---|
Lys 7 | Gln 497 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 21603.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 882.0 | |
All* | Total formula weight | 22485.5 |