3EKU
Crystal Structure of Monomeric Actin bound to Cytochalasin D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Actin-5C | polymer | 375 | 41826.7 | 1 | UniProt (P10987) Pfam (PF00022) | Drosophila melanogaster (Fruit fly) | |
| 2 | B (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 3 | C, D (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | E (A) | (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate | non-polymer | 507.6 | 1 | Chemie (CY9) | |||
| 5 | F (A) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A: 1 - 375 (UniProt: P10987)
| PDB | External Database | Details |
|---|---|---|
| Glu 204 | Ala 205 | engineered mutation |
| Lys 243 | Pro 244 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41826.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1095.0 | |
| All* | Total formula weight | 42921.6 |
