3EKU
Crystal Structure of Monomeric Actin bound to Cytochalasin D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Actin-5C | polymer | 375 | 41826.7 | 1 | UniProt (P10987) Pfam (PF00022) | Drosophila melanogaster (Fruit fly) | |
| 2 | B (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 3 | C, D (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 4 | E (A) | (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate | non-polymer | 507.6 | 1 | Chemie (CY9) PubChem (16760041) PubChem (16760386) PubChem (20055135) PubChem (30956) PubChem (177439595) PubChem (177443560) PubChem (177546129) PubChem (177554437) PubChem (16725079) PubChem (24870973) PubChem (24883743) PubChem (24941110) PubChem (24978555) PubChem (44715324) PubChem (44634700) PubChem (45073470) PubChem (52944149) PubChem (53298510) PubChem (53314889) PubChem (60159013) PubChem (58560015) PubChem (68337917) PubChem (71308557) PubChem (176489236) PubChem (5476249) PubChem (6419417) PubChem (6433799) PubChem (6474112) PubChem (6604835) PubChem (6610334) PubChem (71308181) PubChem (90479773) PubChem (90661723) PubChem (71699760) PubChem (73952838) PubChem (10673207) PubChem (93955376) PubChem (95049224) PubChem (91418974) PubChem (98043243) PubChem (98137101) PubChem (98475982) PubChem (91885930) PubChem (96327550) PubChem (98508109) PubChem (98178182) PubChem (5458428) PubChem (124523547) PubChem (124524852) PubChem (9936028) PubChem (10673206) PubChem (122173078) PubChem (137322830) PubChem (124523548) PubChem (124918412) PubChem (129316905) PubChem (131668624) PubChem (133562887) PubChem (137322831) PubChem (163087539) PubChem (137628527) PubChem (138113437) PubChem (166639690) PubChem (146158182) PubChem (154825569) PubChem (154828159) PubChem (155633784) PubChem (156621406) PubChem (160808448) PubChem (162672469) PubChem (163087537) PubChem (163087538) PubChem (163087540) PubChem (163087541) PubChem (163087542) PubChem (163087543) PubChem (163087544) PubChem (163087545) PubChem (163186922) PubChem (166604442) PubChem (171319297) PubChem (171337492) PubChem (172013425) PubChem (172046909) PubChem (172898048) | |||
| 5 | F (A) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A: 1 - 375 (UniProt: P10987)
| PDB | External Database | Details |
|---|---|---|
| Glu 204 | Ala 205 | engineered mutation |
| Lys 243 | Pro 244 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41826.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1095.0 | |
| All* | Total formula weight | 42921.6 |
