3EGT

T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-722

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Farnesyl pyrophosphate synthase	polymer	413	46936.4	2	UniProt (Q86C09) Pfam (PF00348)	Trypanosoma brucei
2	C, D, E, G, H... (A, B)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
3	F, J (A, B)	1-(2,2-diphosphonoethyl)-3-(heptyloxy)pyridinium	non-polymer		382.3	2	Chemie (722)
4	K, L (A, B)	water	water		18.0	265	Chemie (HOH)

Sequence modifications

A, B: 1 - 367 (UniProt: Q86C09)

PDB	External Database	Details
Met -45	-	expression tag
Gly -44	-	expression tag
Ser -43	-	expression tag
Ser -42	-	expression tag
His -41	-	expression tag
His -40	-	expression tag
His -39	-	expression tag
His -38	-	expression tag
His -37	-	expression tag
His -36	-	expression tag
Ser -35	-	expression tag
Ser -34	-	expression tag
Gly -33	-	expression tag
Leu -32	-	expression tag
Val -31	-	expression tag
Pro -30	-	expression tag
Arg -29	-	expression tag
Gly -28	-	expression tag
Ser -27	-	expression tag
His -26	-	expression tag
Met -25	-	expression tag
Ala -24	-	expression tag
Ser -23	-	expression tag
Met -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	93872.9
Non-Polymers*	Number of molecules	8
	Total formula weight	910.4
All*	Total formula weight	94783.3

*Water molecules are not included.