3EGG
Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Spinophilin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | polymer | 329 | 37349.8 | 2 | UniProt (P62136) Pfam (PF16891) Pfam (PF00149) In PDB | Homo sapiens (Human) | PP-1A |
2 | C, D | Spinophilin | polymer | 170 | 18622.6 | 2 | UniProt (O35274) Pfam (PF17817) Pfam (PF00595) In PDB | Rattus norvegicus (Rat) | Neurabin-II, Neurabin-2, Protein phosphatase 1 regulatory subunit 9B, Neural tissue-specific F-actin-binding protein II, p130, PP1bp134 |
3 | A, B, C, D | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
4 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
5 | A, B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 3 | Chemie (MES) | |||
6 | water | water | 18.0 | 521 | Chemie (HOH) |
Sequence modifications
A, B: 7 - 330 (UniProt: P62136)
C, D: 417 - 583 (UniProt: O35274)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
His -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 111945.0 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1450.1 | |
All* | Total formula weight | 113395.1 |