3EDL

Kinesin13-Microtubule Ring complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tubulin alpha-1A chain	polymer	451	50107.2	1	UniProt (P02550) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P81947)	Bos taurus (bovine)	Alpha-tubulin 1,Tubulin alpha-1 chain
2	B, E (B, G)	Beta tubulin	polymer	445	49907.8	2	UniProt (P02554) Pfam (PF00091) Pfam (PF03953)	Bos taurus (bovine)
3	C (D)	Kinesin-like protein KIF2C	polymer	331	37072.6	1	UniProt (Q922S8) Pfam (PF00225)	Drosophila melanogaster	Mitotic centromere-associated kinesin,MCAK
4	D (F)	Tubulin alpha-1A chain	polymer	451	50163.3	1	UniProt (P02550) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P81947)	Bos taurus (bovine)	Alpha-tubulin 1,Tubulin alpha-1 chain
5	F (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
6	G, K, M (A, D, F)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG) PubChem (888)
7	H, N (B, F)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP) PubChem (135600366) PubChem (135749822) PubChem (136664747) PubChem (136803486) PubChem (164715984) PubChem (135398633) PubChem (135400627) PubChem (135487750) PubChem (135544356) PubChem (135547949) PubChem (136005188) PubChem (136073923) PubChem (136088935) PubChem (136240914) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (171699466)
8	I, O (B, F)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP) PubChem (172898537) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136073927) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074)
9	J (B)	TAXOL	non-polymer		853.9	1	Chemie (TA1) PubChem (101598423) PubChem (124747273) PubChem (126761000) PubChem (129395998) PubChem (46782671) PubChem (4666) PubChem (160585532) PubChem (36314) PubChem (60915) PubChem (163077211) PubChem (167423928) PubChem (177409) PubChem (184492) PubChem (441276) PubChem (118528174) PubChem (121459571) PubChem (5317123) PubChem (5321715) PubChem (5352019) PubChem (122361554) PubChem (124747271) PubChem (124747272) PubChem (124747274) PubChem (124893098) PubChem (6604028) PubChem (6604616) PubChem (6604814) PubChem (6713921) PubChem (6915727) PubChem (126968948) PubChem (129627423) PubChem (9875988) PubChem (132517454) PubChem (133052515) PubChem (133640187) PubChem (134368714) PubChem (134715514) PubChem (134972678) PubChem (10033513) PubChem (10485732) PubChem (10748131) PubChem (11320430) PubChem (11354895) PubChem (11506104) PubChem (11828953) PubChem (14060298) PubChem (14060299) PubChem (14060304) PubChem (14060306) PubChem (137705323) PubChem (138106885) PubChem (15983941) PubChem (16742549) PubChem (16757828) PubChem (16760177) PubChem (16760674) PubChem (21733096) PubChem (140512017) PubChem (140731501) PubChem (143890766) PubChem (144453087) PubChem (146034004) PubChem (23307219) PubChem (23307242) PubChem (23307253) PubChem (23307913) PubChem (23412627) PubChem (23636632) PubChem (24207713) PubChem (24754091) PubChem (24791027) PubChem (152743329) PubChem (153289350) PubChem (154037993) PubChem (154828192) PubChem (155982214) PubChem (24848897) PubChem (24867246) PubChem (25200067) PubChem (159121804) PubChem (159716711) PubChem (160053861) PubChem (160171678) PubChem (160585530) PubChem (42613129) PubChem (42620039) PubChem (44155032) PubChem (44276363) PubChem (44279927) PubChem (44291178) PubChem (44328863) PubChem (44335735) PubChem (44342632) PubChem (44356895) PubChem (44378736) PubChem (44403716) PubChem (45489039) PubChem (46781469) PubChem (57489669) PubChem (57908851) PubChem (57946364) PubChem (57999380) PubChem (58460861) PubChem (58596717) PubChem (58777027) PubChem (58798493) PubChem (58803237) PubChem (58877402) PubChem (49868078) PubChem (163077209) PubChem (163077210) PubChem (163077212) PubChem (163077213) PubChem (163077214) PubChem (163077215) PubChem (163284947) PubChem (53298534) PubChem (53313247) PubChem (165084161) PubChem (54259297) PubChem (54259298) PubChem (54259299) PubChem (166711459) PubChem (168322423) PubChem (169917882) PubChem (170014955) PubChem (59042813) PubChem (59048611) PubChem (170362150) PubChem (171036874) PubChem (5460441) PubChem (59844545) PubChem (59873251) PubChem (59904698) PubChem (59919147) PubChem (60005248) PubChem (60011010) PubChem (60123436) PubChem (60123443) PubChem (60147315) PubChem (66795656) PubChem (175758871) PubChem (70801836) PubChem (70842048) PubChem (70848451) PubChem (70856170) PubChem (70943371) PubChem (71096818) PubChem (71209844) PubChem (9854162) PubChem (9897470) PubChem (73707502) PubChem (73759704) PubChem (73759783) PubChem (89493063) PubChem (89847578) PubChem (90057663) PubChem (91122402) PubChem (14060309) PubChem (91885464) PubChem (21458255) PubChem (101920282) PubChem (44323108) PubChem (44356961) PubChem (59914794) PubChem (176586897)
10	L (D)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP) PubChem (4795) PubChem (33113) PubChem (445863) PubChem (6102784) PubChem (9543492) PubChem (14188278) PubChem (16058657) PubChem (23639785) PubChem (24794410) PubChem (44462678) PubChem (46926537) PubChem (54765332) PubChem (60063697) PubChem (66575078) PubChem (89688694) PubChem (92436779) PubChem (93005803)
11	P (G)	2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE	non-polymer		431.5	1	Chemie (CN2) PubChem (21158775) PubChem (5287955)
12	Q, R (D, F)	water	water		18.0	107	Chemie (HOH)

Sequence modifications

A: 1 - 451 (UniProt: P02550)

PDB	External Database	Details
Gly 265	Ala 265	conflict

F: 1 - 451 (UniProt: P02550)

PDB	External Database	Details
Ile 265	Ala 265	conflict

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	237158.7
Non-Polymers*	Number of molecules	11
	Total formula weight	3862.7
All*	Total formula weight	241021.4

*Water molecules are not included.