3EC0
High Resolution HIV-2 Protease Structure in Complex with Antiviral Inhibitor GRL-06579A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10728.3 | 2 | UniProt (P04584) Pfam (PF00077) | Human immunodeficiency virus type 2 (ISOLATE ROD) | |
| 2 | C (A) | (3AS,5R,6AR)-HEXAHYDRO-2H-CYCLOPENTA[B]FURAN-5-YL (2S,3S)-3-HYDROXY-4-(4-(HYDROXYMETHYL)-N-ISOBUTYLPHENYLSULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE | non-polymer | 560.7 | 1 | Chemie (GRL) | |||
| 3 | D, E, M, N, O... (A, B) | IMIDAZOLE | non-polymer | 69.1 | 6 | Chemie (IMD) | |||
| 4 | F, G, H, I, Q... (A, B) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 5 | AA, BA, J, K, W... (B, A) | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) | |||
| 6 | L (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | CA, DA (A, B) | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21456.7 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 1935.9 | |
| All* | Total formula weight | 23392.6 |
