3EBZ
High Resolution HIV-2 Protease Structure in Complex with Clinical Drug Darunavir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10728.3 | 2 | UniProt (P04584) | Human immunodeficiency virus type 2 (ISOLATE ROD) | |
| 2 | C, D, K, L, M... (A, B) | IMIDAZOLE | non-polymer | 69.1 | 6 | Chemie (IMD) | |||
| 3 | E, F, G, O, P... (A, B) | ZINC ION | non-polymer | 65.4 | 9 | Chemie (ZN) | |||
| 4 | AA, H, U, V, W... (B, A) | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) PubChem (312) | |||
| 5 | I (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 6 | J (B) | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | non-polymer | 547.7 | 1 | Chemie (017) PubChem (213039) PubChem (23545473) PubChem (44400512) PubChem (44578485) PubChem (52949690) PubChem (58330571) PubChem (60170302) PubChem (70329566) PubChem (66725685) PubChem (3001874) PubChem (6320436) PubChem (6320437) PubChem (89334570) PubChem (89394603) PubChem (102206609) PubChem (6320435) PubChem (101897907) PubChem (125136514) PubChem (102206607) PubChem (102206608) PubChem (118243427) PubChem (118243428) PubChem (118243429) PubChem (125136515) PubChem (129010372) PubChem (131632443) PubChem (131667685) PubChem (134694394) PubChem (137704505) PubChem (137704865) PubChem (138631483) PubChem (138631484) PubChem (138631622) PubChem (144227995) PubChem (145507139) PubChem (147231834) PubChem (156183881) PubChem (156183911) PubChem (171370671) | |||
| 7 | BA, CA (A, B) | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21456.7 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 1857.5 | |
| All* | Total formula weight | 23314.1 |
