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3EB1

Crystal structure PTP1B complex with small molecule inhibitor LZP-25

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATyrosine-protein phosphatase non-receptor type 1polymer32137365.61UniProt (P18031)
Pfam (PF00102)
In PDB
Homo sapiens (Human)Protein-tyrosine phosphatase 1B, PTP-1B
2A4-[3-(dibenzylamino)phenyl]-2,4-dioxobutanoic acidnon-polymer387.41Chemie (LZQ)
3waterwater18.0157Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37365.6
Non-Polymers*Number of molecules1
Total formula weight387.4
All*Total formula weight37753.1
*Water molecules are not included.

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PDB entries from 2024-04-24

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