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3E7I

Structure of murine inos oxygenase domain with inhibitor AR-C94864

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Nitric oxide synthase, induciblepolymer43350121.02UniProt (P29477)
Pfam (PF02898)
Mus musculus (mouse)NOS TYPE II, INDUCIBLE NOS, INOS, MACROPHAGE NOS, MAC-NOS
2C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
3D, I
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
4E, J
(A, B)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.52Chemie (HEM)
5F, K
(A, B)
5,6,7,8-TETRAHYDROBIOPTERINnon-polymer241.22Chemie (H4B)
6G, H, L
(A, B)
(2R)-5-FLUORO-2-(2-THIENYL)-1,2-DIHYDROQUINAZOLIN-4-AMINEnon-polymer247.33Chemie (B2)
7M, N
(A, B)
waterwater18.0191Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight100241.9
Non-Polymers*Number of molecules10
Total formula weight2684.2
All*Total formula weight102926.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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