3E4E
Human cytochrome P450 2E1 in complex with the inhibitor 4-methylpyrazole
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Cytochrome P450 2E1 | polymer | 476 | 55058.5 | 2 | UniProt (P05181) Pfam (PF00067) In PDB | Homo sapiens (Human) | CYPIIE1, P450-J |
2 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
3 | A, B | 4-methyl-1H-pyrazole | non-polymer | 82.1 | 2 | Chemie (4PZ) | |||
4 | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A, B: 32 - 493 (UniProt: P05181)
PDB | External Database | Details |
---|---|---|
Met 22 | - | expression tag |
Ala 23 | - | expression tag |
Lys 24 | - | expression tag |
Lys 25 | - | expression tag |
Thr 26 | - | expression tag |
Ser 27 | - | expression tag |
Ser 28 | - | expression tag |
Lys 29 | - | expression tag |
Gly 30 | - | expression tag |
Lys 31 | - | expression tag |
His 494 | - | expression tag |
His 495 | - | expression tag |
His 496 | - | expression tag |
His 497 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 110117.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1397.2 | |
All* | Total formula weight | 111514.2 |