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3E46

Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington interacting protein 2) M172A mutant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ubiquitin-conjugating enzyme E2-25 kDapolymer25328205.81UniProt (P61086)
Pfam (PF00179)
Pfam (PF00627)
Homo sapiensUbiquitin-conjugating enzyme E2 K, E2(25K), Ubiquitin-protein ligase, Ubiquitin carrier protein, Huntingtin-interacting protein 2, HIP-2
2B
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
3C
(A)
waterwater18.0207Chemie (HOH)
Sequence modifications
A: 1 - 200 (UniProt: P61086)
PDBExternal DatabaseDetails
Met -52-expression tag
His -51-expression tag
His -50-expression tag
His -49-expression tag
His -48-expression tag
His -47-expression tag
His -46-expression tag
Ser -45-expression tag
Ser -44-expression tag
Gly -43-expression tag
Leu -42-expression tag
Val -41-expression tag
Pro -40-expression tag
Arg -39-expression tag
Gly -38-expression tag
Ser -37-expression tag
Gly -36-expression tag
Met -35-expression tag
Lys -34-expression tag
Glu -33-expression tag
Thr -32-expression tag
Ala -31-expression tag
Ala -30-expression tag
Ala -29-expression tag
Lys -28-expression tag
Phe -27-expression tag
Glu -26-expression tag
Arg -25-expression tag
Gln -24-expression tag
His -23-expression tag
Met -22-expression tag
Asp -21-expression tag
Ser -20-expression tag
Pro -19-expression tag
Asp -18-expression tag
Leu -17-expression tag
Gly -16-expression tag
Thr -15-expression tag
Asp -14-expression tag
Asp -13-expression tag
Asp -12-expression tag
Asp -11-expression tag
Lys -10-expression tag
Ala -9-expression tag
Met -8-expression tag
Ala -7-expression tag
Asp -6-expression tag
Ile -5-expression tag
Gly -4-expression tag
Ser -3-expression tag
Glu -2-expression tag
Phe -1-expression tag
Asp 0-expression tag
Ala 172Met 172engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28205.8
Non-Polymers*Number of molecules1
Total formula weight40.1
All*Total formula weight28245.9
*Water molecules are not included.

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PDB entries from 2024-10-30

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