3E46
Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington interacting protein 2) M172A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin-conjugating enzyme E2-25 kDa | polymer | 253 | 28205.8 | 1 | UniProt (P61086) Pfam (PF00179) Pfam (PF00627) | Homo sapiens | Ubiquitin-conjugating enzyme E2 K, E2(25K), Ubiquitin-protein ligase, Ubiquitin carrier protein, Huntingtin-interacting protein 2, HIP-2 |
| 2 | B (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | C (A) | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence modifications
A: 1 - 200 (UniProt: P61086)
| PDB | External Database | Details |
|---|---|---|
| Met -52 | - | expression tag |
| His -51 | - | expression tag |
| His -50 | - | expression tag |
| His -49 | - | expression tag |
| His -48 | - | expression tag |
| His -47 | - | expression tag |
| His -46 | - | expression tag |
| Ser -45 | - | expression tag |
| Ser -44 | - | expression tag |
| Gly -43 | - | expression tag |
| Leu -42 | - | expression tag |
| Val -41 | - | expression tag |
| Pro -40 | - | expression tag |
| Arg -39 | - | expression tag |
| Gly -38 | - | expression tag |
| Ser -37 | - | expression tag |
| Gly -36 | - | expression tag |
| Met -35 | - | expression tag |
| Lys -34 | - | expression tag |
| Glu -33 | - | expression tag |
| Thr -32 | - | expression tag |
| Ala -31 | - | expression tag |
| Ala -30 | - | expression tag |
| Ala -29 | - | expression tag |
| Lys -28 | - | expression tag |
| Phe -27 | - | expression tag |
| Glu -26 | - | expression tag |
| Arg -25 | - | expression tag |
| Gln -24 | - | expression tag |
| His -23 | - | expression tag |
| Met -22 | - | expression tag |
| Asp -21 | - | expression tag |
| Ser -20 | - | expression tag |
| Pro -19 | - | expression tag |
| Asp -18 | - | expression tag |
| Leu -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Thr -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Lys -10 | - | expression tag |
| Ala -9 | - | expression tag |
| Met -8 | - | expression tag |
| Ala -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Ile -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Glu -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Ala 172 | Met 172 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28205.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 28245.9 |
