3E3B
Crystal structure of catalytic subunit of human protein kinase CK2alpha prime with a potent indazole-derivative inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | Casein kinase II subunit alpha' | polymer | 339 | 40160.0 | 1 | UniProt (P19784) Pfam (PF00069) | Homo sapiens (Human) | casein kinase CK2 alpha prime, CK II |
| 2 | B (X) | [1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid | non-polymer | 376.4 | 1 | Chemie (CCK) | |||
| 3 | C (X) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
X: 1 - 334 (UniProt: P19784)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40160.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 376.4 | |
| All* | Total formula weight | 40536.4 |
