3E1I
Crystal Structure of BbetaD432A Variant Fibrinogen Fragment D with the Peptide Ligand Gly-His-Arg-Pro-amide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Fibrinogen alpha chain | polymer | 87 | 10245.0 | 2 | UniProt (P02671) Pfam (PF08702) | Homo sapiens (human) | Fibrinopeptide A |
| 2 | B, E (B, E) | Fibrinogen beta chain | polymer | 328 | 37648.0 | 2 | UniProt (P02675) Pfam (PF08702) Pfam (PF00147) | Homo sapiens (human) | Fibrinopeptide B |
| 3 | C, F (C, F) | Fibrinogen gamma chain | polymer | 319 | 36223.3 | 2 | UniProt (P02679) Pfam (PF08702) Pfam (PF00147) | Homo sapiens (human) | |
| 4 | G, H (G, H) | Gly-His-Arg-Pro-amide | polymer | 5 | 465.5 | 2 | synthetic construct | ||
| 5 | I, N (B, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | J, K, L, M, O... (B, C, E, F) | CALCIUM ION | non-polymer | 40.1 | 7 | Chemie (CA) | |||
| 7 | R, S, T, U, V... (A, B, C, D, E...) | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence modifications
B, E: 134 - 461 (UniProt: P02675)
| PDB | External Database | Details |
|---|---|---|
| Ala 432 | Asp 462 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 169163.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 723.0 | |
| All* | Total formula weight | 169886.5 |
