3E1I
Crystal Structure of BbetaD432A Variant Fibrinogen Fragment D with the Peptide Ligand Gly-His-Arg-Pro-amide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | Fibrinogen alpha chain | polymer | 87 | 10245.0 | 2 | UniProt (P02671) Pfam (PF08702) In PDB | Homo sapiens (human) | Fibrinopeptide A |
2 | B, E | Fibrinogen beta chain | polymer | 328 | 37648.0 | 2 | UniProt (P02675) Pfam (PF08702) Pfam (PF00147) In PDB | Homo sapiens (human) | Fibrinopeptide B |
3 | C, F | Fibrinogen gamma chain | polymer | 319 | 36223.3 | 2 | UniProt (P02679) Pfam (PF08702) Pfam (PF00147) In PDB | Homo sapiens (human) | |
4 | G, H | Gly-His-Arg-Pro-amide | polymer | 5 | 465.5 | 2 | synthetic construct | ||
5 | B, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
6 | B, C, E, F | CALCIUM ION | non-polymer | 40.1 | 7 | Chemie (CA) | |||
7 | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence modifications
B, E: 134 - 461 (UniProt: P02675)
PDB | External Database | Details |
---|---|---|
Ala 432 | Asp 462 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 169163.5 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 723.0 | |
All* | Total formula weight | 169886.5 |