3E0W

Crystal structure of pyruvate kinase from Leishmania mexicana

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Pyruvate kinase	polymer	539	58867.8	1	UniProt (Q27686) Pfam (PF00224) Pfam (PF02887)	Leishmania mexicana	PK
2	B (A)	water	water		18.0	75	Chemie (HOH)

Sequence modifications

A: 0 - 498 (UniProt: Q27686)

PDB	External Database	Details
Met -40	-	expression tag
Gly -39	-	expression tag
Ser -38	-	expression tag
Ser -37	-	expression tag
His -36	-	expression tag
His -35	-	expression tag
His -34	-	expression tag
His -33	-	expression tag
His -32	-	expression tag
His -31	-	expression tag
Ser -30	-	expression tag
Ser -29	-	expression tag
Gly -28	-	expression tag
Leu -27	-	expression tag
Val -26	-	expression tag
Pro -25	-	expression tag
Arg -24	-	expression tag
Gly -23	-	expression tag
Ser -22	-	expression tag
His -21	-	expression tag
Met -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Ser 382	Gly 383	conflict
Tyr 389	Ser 390	conflict
Arg 404	Ala 405	conflict
Ser 405	Gly 406	conflict
Trp 451	Glu 452	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	58867.8
All*	Total formula weight	58867.8

*Water molecules are not included.