3DXA
Crystal Structure of the DM1 TCR in complex with HLA-B*4405 and decamer EBV antigen
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, K (A, F, K) | HLA class I histocompatibility complex HLA-B*4402 | polymer | 276 | 32028.3 | 3 | UniProt (P30481) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889) | Homo sapiens (human) | HLA class I histocompatibility antigen, B-44 alpha chain ; MHC class I antigen B*44; Bw-44 |
| 2 | B, G, L (B, G, L) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 3 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | C, H, M (C, H, M) | EBV decapeptide epitope | polymer | 10 | 1282.4 | 3 | UniProt (P03204) | ||
| 4 | D, I, N (D, I, N) | DM1 T cell receptor alpha chain | polymer | 199 | 22255.7 | 3 | Pfam (PF09291) UniProt (by SIFTS) (P01848) | Homo sapiens (human) | |
| 5 | E, J, O (E, J, O) | DM1 T cell receptor beta chain | polymer | 244 | 28139.2 | 3 | Homo sapiens (human) |
Sequence modifications
A, F, K: 1 - 276 (UniProt: P30481)
| PDB | External Database | Details |
|---|---|---|
| Tyr 116 | Asp 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 286361.6 | |
| All* | Total formula weight | 286361.6 |
