3DX8
Crystal Structure of B*4405 presenting a 10mer EBV epitope
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility complex HLA-B*4405 | polymer | 276 | 32028.3 | 1 | UniProt (P30481) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889) | Homo sapiens (human) | HLA class I histocompatibility antigen, B-44 alpha chain ; MHC class I antigen B*44; Bw-44 |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | C (C) | EBV decapeptide epitope | polymer | 10 | 1282.4 | 1 | UniProt (P03204) | ||
| 4 | D, E (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F, G, H (A, B, C) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: P30481)
| PDB | External Database | Details |
|---|---|---|
| Tyr 116 | Asp 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 45058.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 45243.1 |
