3DWJ
Heme-proximal W188H mutant of inducible nitric oxide synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nitric oxide synthase, inducible | polymer | 431 | 49829.7 | 2 | UniProt (P29477) Pfam (PF02898) | Mus musculus (mouse) | NOS type II, Inducible NO synthase, Inducible NOS, iNOS, Macrophage NOS, MAC- NOS |
| 2 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | D, G (A, B) | AMMONIUM ION | non-polymer | 18.0 | 2 | Chemie (NH4) | |||
| 4 | E, H (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 5 | F, I (A, B) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence modifications
A, B: 66 - 496 (UniProt: P29477)
| PDB | External Database | Details |
|---|---|---|
| His 188 | Trp 188 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 99659.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1847.6 | |
| All* | Total formula weight | 101507.0 |
