3DV0
Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Pyruvate dehydrogenase E1 component subunit alpha | polymer | 369 | 41518.2 | 4 | UniProt (P21873) Pfam (PF00676) | Bacillus stearothermophilus | |
| 2 | B, D, F, H (B, D, F, H) | Pyruvate dehydrogenase E1 component subunit beta | polymer | 325 | 35495.6 | 4 | UniProt (P21874) Pfam (PF02779) Pfam (PF02780) | Bacillus stearothermophilus | |
| 3 | I, J (I, J) | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | polymer | 428 | 46392.2 | 2 | UniProt (P11961) Pfam (PF00364) Pfam (PF02817) Pfam (PF00198) | Bacillus stearothermophilus | E2, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex |
| 4 | K, N, P, U, W... (A, B, C, E, G) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 5 | L, Q, T, X (A, C, E, G) | 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL TRIHYDROGEN DIPHOSPHATE | non-polymer | 423.3 | 4 | Chemie (TPW) | |||
| 6 | M, R, V, Z (B, D, F, H) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 7 | O, S (B, D) | PYRUVIC ACID | non-polymer | 88.1 | 2 | Chemie (PYR) | |||
| 8 | AA, BA, CA, DA, EA... (A, B, C, D, E...) | water | water | 18.0 | 990 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 400839.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2171.6 | |
| All* | Total formula weight | 403011.3 |
