3DU8
Crystal structure of GSK-3 beta in complex with NMS-869553A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycogen synthase kinase-3 beta | polymer | 422 | 46955.4 | 2 | UniProt (P49841) Pfam (PF00069) | Homo sapiens | GSK-3 beta |
| 2 | C, D (A, B) | (7S)-2-(2-aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one | non-polymer | 275.3 | 2 | Chemie (553) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 420 (UniProt: P49841)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 93910.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 550.6 | |
| All* | Total formula weight | 94461.3 |
