3DTQ

Engineered human lipocalin 2 with specificity for Y-DTPA, apo-form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Neutrophil gelatinase-associated lipocalin	polymer	186	21302.1	3	UniProt (P80188) Pfam (PF00061)	Homo sapiens (human)	NGAL, p25, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3
2	D, E, F (A, B, C)	water	water		18.0	487	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 178 (UniProt: P80188)

PDB	External Database	Details
His 28	Gln 48	engineered mutation
Gln 33	Val 53	engineered mutation
Arg 36	Leu 56	engineered mutation
Ala 41	Ile 61	engineered mutation
Thr 52	Tyr 72	engineered mutation
Gln 54	Thr 74	engineered mutation
Ala 68	Ser 88	engineered mutation
Arg 70	Leu 90	engineered mutation
Ala 79	Trp 99	engineered mutation
Thr 80	Ile 100	engineered mutation
Met 81	Arg 101	engineered mutation
Ser 87	Cys 107	engineered mutation
Ser 134	Lys 154	engineered mutation
Leu 138	Tyr 158	engineered mutation
Ala 145	Thr 165	engineered mutation
Ser 179	-	expression tag
Ala 180	-	expression tag
His 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	63906.3
All*	Total formula weight	63906.3

*Water molecules are not included.